Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients with Patent Foramen Ovale (REDUCE PAS)

Study to evaluate closing the patent foramen ovale (PFO) [a small opening in the heart] by using a medical device called the GORE CARDIOFORM Septal Occluder in order to reduce your risk of another stroke.

In order to participate you must meet the following criteria:

• Are 18-70 years of age.
• Have been evaluated by a neurologist and diagnosed with an ischemic stroke presumed to be an embolic stroke of undetermined source (ESUS) within the last 455 days.
• Have the presence of a PFO.
• Are able to tolerate antiplatelet therapy.

You will be excluded from the study if any of the following criteria apply to you: 

• Have a history of or ongoing atrial fibrillation/flutter.
• Have had a previous myocardial infarction [heart attack].
• Have an active infection that cannot be treated successfully.
• Have uncontrolled systemic hypertension and uncontrolled diabetes mellitus.

This is a partial list of eligibility requirements. To inquire about your eligibility, please call the contact number provided. If you wish to inquire via email, please include the title of the study in your message.